Abstract
Epigenetic modifications include histone modifications (acetylation, methylation, sulphonation, ubiquitination, etc.), DNA methylation (particularly cytosine methylation), and ncRNAs including miRNAs (microRNAs), lncRNAs (long non‐coding RNAs) and circRNA (circular RNAs). Each of these modifications influences gene expression in a regulated manner influencing phenotypes including response to biotic and abiotic stresses. Disease resistance is one such trait, which is influenced by epigenetic modifications. A variety of techniques are available for the study of each of these epigenetic modifications, and each technique involves DNA sequencing followed by analysis of sequenced data using a variety of bioinformatics tools. In this chapter, we discuss different types of epigenetic modifications and the bioinformatics tools for analysis of these epigenetic modifications, with particular emphasis on disease resistance.