Book chapter
Classical swine fever virus vaccine stability in Lao PDR
Management of classical swine fever and foot-and-mouth disease in Lao PDR : proceedings of an international workshop held in Vientiane, Lao PDR, 20-21 November 2006. ACIAR Proceedings No. 128, pp.80-83
ACIAR
2008
Abstract
Classical swine fever (CSF) virus is a highly contagious but vaccine-preventable disease of swine. A locally produced lapinised C-strain vaccine is used to control CSF in Lao PDR; however, vaccine failure has been reported. The CSF vaccine is produced at the National Vaccine Production Centre (NVPC) as a freeze-dried rabbit spleen homogenate in a rubber stoppered glass vial and stored at –20 °C with a recommended shelf life of 1 year. This paper describes two studies to (i) determine the stability of the locally produced vaccine when stored at 4 °C and –20 °C and (ii) determine if the vaccine elicits a protective immune response when delivered to village pigs under good transport conditions. The vaccine was found to be stable for only 4 months when stored at –20 °C and for less than 3 months when stored at 4 °C. Under field conditions, vaccine stored at –20 °C for 2 months and transported at temperatures less than 1 °C elicited an immune response in 89% of vaccinated pigs by day 35 and 100% of pigs by day 70 post vaccination.
Details
- Title
- Classical swine fever virus vaccine stability in Lao PDR
- Authors/Creators
- J. Conlan (Author/Creator)T. Vitesnik (Author/Creator)S. Khounsy (Author/Creator)C. Wilks (Author/Creator)L. Gleeson (Author/Creator)
- Contributors
- J. Conlan (Editor)S. Blacksell (Editor)C. Morrissy (Editor)A. Colling (Editor)
- Publication Details
- Management of classical swine fever and foot-and-mouth disease in Lao PDR : proceedings of an international workshop held in Vientiane, Lao PDR, 20-21 November 2006. ACIAR Proceedings No. 128, pp.80-83
- Publisher
- ACIAR; Canberra, Australia
- Identifiers
- 991005542994007891
- Copyright
- © Commonwealth of Australia 2008
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Book chapter
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