Book chapter
Hormones and Perinatal Development
Hormonal Signaling in Biology and Medicine, pp.1-11
Academic Press
2020
Abstract
The stimulatory or inhibitory effects of numerous hormones are required for many perinatal developmental events that are essential for postnatal survival. These developmental processes include the acquisition of gluconeogenesis, amino acid catabolism, and urea biosynthetic capacity in the neonatal liver; perinatal lung maturation; and alterations to digestive enzyme capabilities upon weaning. Much of our understanding of the mechanisms underlying regulation of the relevant biochemical pathways stems from the cloning of critical genes. Transcription factor motifs and enhancer sequences have been identified in their promoter regions, which are involved in regulating their expression and their perinatal appearance. Although enhanced expression of these genes, which leads to improved metabolic capacity and versatility of the tissues, is primarily the result of de novo transcription, there is compelling evidence that posttranscriptional mechanisms can also contribute.
Details
- Title
- Hormones and Perinatal Development
- Authors/Creators
- M.H. Cake (Author/Creator) - Murdoch UniversityG.C.T. Yeoh (Author/Creator) - Harry Perkins Institute of Medical Research
- Contributors
- G. Litwack (Editor)
- Publication Details
- Hormonal Signaling in Biology and Medicine, pp.1-11
- Publisher
- Academic Press
- Identifiers
- 991005540448107891
- Copyright
- © 2020 Elsevier Inc.
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Book chapter
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