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Review
Exploring The Health Benefits of Ganoderma; Hepatoprotective and Cardiovascular Effects and Mechanisms of Action
CHIANG MAI JOURNAL OF SCIENCE, Vol.52(3), 2025028
2025
Abstract
Liver diseases, which encompass a wide spectrum from liver inflammation to hepatotoxicity, represent significant global health concerns due to their prevalence and severe health impacts. Extracts derived from Ganoderma species, renowned for their medicinal properties, have emerged as promising candidates for hepatoprotection. These extracts have shown efficacy in mitigating liver damage caused by various factors, such as toxins (e.g., alcohol, certain medications) and infections (e.g., hepatitis viruses). In addition, they demonstrate potential in reducing inflammatory responses within the liver and promoting its regeneration- key aspects of maintaining liver health. Furthermore, Ganoderma holds notable implications for cardiovascular health. Studies have highlighted its abilityto modulate blood lipid profiles, potentially lowering cholesterol levels and reducing the risk of cardiovascular diseases. It also enhances endothelial function, which is critical for maintaining vascular health and regulating blood flow. Moreover, the anti-oxidant properties of Ganoderma help alleviate oxidative stress, a key factor implicated in cardiovascular diseases. The combination of these therapeutic attributes positions Ganoderma as a promising agent not only for managing liver-related ailments but also for addressing cardiovascular disorders. This emphasis on the potential of Ganoderma fosters optimism about future treatments. However, comprehensive investigations are needed to fully elucidate the precise mechanisms underlying its hepatoprotective and cardiovascular effects. The potential for future discoveries in this area is substantial, and a deeper understanding of these mechanisms will be crucial for optimizing dosage regimens and unlocking the full clinical potential of Ganoderma in treating liver and cardiovascular conditions.
Details
- Title
- Exploring The Health Benefits of Ganoderma; Hepatoprotective and Cardiovascular Effects and Mechanisms of Action
- Authors/Creators
- Samantha Chandranath Karunarathna - Qujing Normal UniversityNimesha Patabendige - Murdoch UniversityKalani Kanchana Hapuarachchi - Southwest Forestry University
- Publication Details
- CHIANG MAI JOURNAL OF SCIENCE, Vol.52(3), 2025028
- Publisher
- Chiang Mai University
- Number of pages
- 64
- Grant note
- Key Laboratory of Yunnan Provincial Department of Education of the Deep-Time Evolution on Biodiversity from the Origin of the Pearl River Yunnan Revitalization Talents Support Plan (High-End Foreign Experts Program) 32260004 / National NaturalScience Foundation of China; National Natural Science Foundation of China (NSFC)
- Identifiers
- 991005791873507891
- Copyright
- © Since 2021 All Rights Reserved by Chiang Mai Journal of Science
- Murdoch Affiliation
- School of Medical, Molecular and Forensic Sciences
- Language
- English
- Resource Type
- Review
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- 3 Agriculture, Environment & Ecology
- 3.16 Phytochemicals
- 3.16.698 Polysaccharide Bioactivities
- Web Of Science research areas
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- ESI research areas
- Clinical Medicine