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A monoclonal antibody reacting with the cell envelope of spirochaetes from intestinal spirochaetosis
Conference paper   Open access

A monoclonal antibody reacting with the cell envelope of spirochaetes from intestinal spirochaetosis

B.J. Lee and D.J. Hampson
Proceedings of the 13th International Pig Veterinary Society Congress (Bangkok, Thailand, 26/06/1994–30/06/1994)
1994
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Abstract

Intestinal spirochaetosis results from infection with weakly haemolytic spirochaetes that are distinct from both Serpulina hyodysenteriae and Serpulina innocens (1, 2, 3). These bacteria only have 4-6 axial flagellae, and, belong to a newly-recognised genetic group with the proposed name "Anguillina. coli" ( 3). Disease is mainly seen in weaner and grower pigs, which develop a sloppy mucoid diarrhoea and suffer a reduction in weight gain ( 1). Similar bacteria are associated with intestinal spirochaetosis in humans (4). The purpose of the present work was to prepare and characterise a specific monoclonal antibody that could be used to identify isolates of "A. coli" in the faeces of affected individuals.

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