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Colonic antibody responses in pigs with swine dysentery
Conference paper   Open access

Colonic antibody responses in pigs with swine dysentery

Y. Song and D.J. Hampson
Australasian Pig Science Association
Manipulating Pig Production XII. Proceedings of the 12th Australasian Pig Science Association (APSA) Biennial Conference (Werribee, Australia, 22/11/2009–25/11/2009)
2009
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Abstract

Swine dysentery (SD) is a mucohaemorrhagic colitis of pigs resulting from infection of the large intestine with the anaerobic intestinal spirochaete Brachyspira hyodysenteriae. The infection has been reported to result in the development of specific IgG, IgA and IgM antibodies in serum and the production of secretory IgA in the gut mucosa (Rees et al., 1989). The hypothesis tested in this experiment was that colonic antibody levels can be used as a diagnostic tool to assist the diagnosis of SD. The experimental design involved testing samples from non-infected pigs to define appropriate cut-off values for the assays, and then using these in assays of serum and colonic samples from pigs that had been experimentally exposed to B. hyodysenteriae.

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