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6-aminonicotinamide enhances the radiosensitizing effects of 2-deoxy-d-glucose in ehrlich ascites tumor bearing mice
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6-aminonicotinamide enhances the radiosensitizing effects of 2-deoxy-d-glucose in ehrlich ascites tumor bearing mice

R. Varshney, J.S. Adhikari, V.P. Singh and B.S. Dwarakanath
International Conference on Recent Trends in Radiation Biology (Mumbai, India, 01/12/2004–03/12/2004)
2004

Abstract

Enhanced radiosensitizing effects of a combination of 2-DG and 6-aminonicotinamide (6-AN) an analogue of nicotinamide, which inhibits HMP shunt have been demonstrated in vitro. Purpose of the present studies was to investigate the in vivo effects of this combination in Ehrlich ascites tumor (EAT) bearing mice

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