Conference presentation
Bayesian population genetics and the human history of China
11th Conference of the International Society for Computational Biology (Brisbane, QLD, 29/06/2003–03/07/2003)
2003
Abstract
Throughout recorded Chinese history, regions of the country populated by persons of non-Han ancestry fluctuated significantly in numbers and in terms of their political and commercial influence. Many of these communities had moved from their homelands, settled in China, intermarried with Han Chinese and subsequently formed separate minority populations. Thus the human history of China in large part reflects the impact of migration, population admixture and community endogamy. To assess the possible consequence of these three factors on the current genetic structure of PR China, DNA samples from the majority Han, the Muslim Hui, Bo'an, Dongxiang and Salar, and the more ancient Kuchong, Miao, and Yao minority populations were studied using uniparental and biparental markers. Bayesian algorithms, such as those employed in the program STRUCTURE, were utilised in processing the generated data. The results were compared to analyses utilising more traditional methods such as AMOVA and F-statistics. With both 'traditional' and Bayesian methods, the uniparental and biparental markers exhibited evidence of female gene flow, community endogamy and differing male ancestral origins in the study populations. The results indicate that single marker systems are of limited value in defining population origins and relationships on a historical scale. It is suggested that the future application and development of Bayesian analysis to the study of human genetic diversity should include modelling that accounts for multiple-system data, and non-genetic factors such as recent historical, demographic and cultural effects.
Details
- Title
- Bayesian population genetics and the human history of China
- Authors/Creators
- M.L. Black (Author/Creator)C.A. Wise (Author/Creator)W. Wang (Author/Creator)A.H. Bittles (Author/Creator)
- Conference
- 11th Conference of the International Society for Computational Biology (Brisbane, QLD, 29/06/2003–03/07/2003)
- Identifiers
- 991005541436907891
- Murdoch Affiliation
- Centre for Comparative Genomics
- Language
- English
- Resource Type
- Conference presentation
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