Conference presentation
Cutting edge tools for phenotyping and characterising T-Cell subsets
Science on the Swan 2016 (Perth, Western Australia, 02/05/2016–05/05/2016)
2016
Abstract
Next generation Sequencing (NGS) has enabled high throughput analysis of T cell receptor (TCR) repertoires, which are useful for monitoring antigen- specific T cell responses. Integrating TCR sequencing with expression levels of genes that characterise T cell phenotype at the single cell level allows comprehensive analysis of T cell function and specificity. Single cell TCR sequencing on the Illumina platform enables the identification of paired TCR α/β chains and T cell phenotype from sorted antigen-specific T cell populations. Here we highlight novel techniques available for T cell phenotyping and TCR repertoire analysis.
Details
- Title
- Cutting edge tools for phenotyping and characterising T-Cell subsets
- Authors/Creators
- A. Chopra (Author/Creator)S. Gaudieri (Author/Creator)M. Pilkington (Author/Creator)J. Blinco (Author/Creator)S. Leary (Author/Creator)D. Cooper (Author/Creator)C. Abana (Author/Creator)M. Watson (Author/Creator)S. Kalams (Author/Creator)S. Mallal (Author/Creator)
- Conference
- Science on the Swan 2016 (Perth, Western Australia, 02/05/2016–05/05/2016)
- Identifiers
- 991005544394807891
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Conference presentation
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