Thesis
Co-extraction methods of DNA and total RNA for body fluid identification: A review
Masters by Coursework, Murdoch University
2020
Abstract
Body fluid identification is a crucial step in forensic investigation, and investigators have used various techniques. With the discovery of cell-specific mRNA and miRNA markers as well as their stability in certain conditions, co-analysis of DNA and RNA from the same sample is possible and can bring multiple benefits. The workflow can be streamlined and the frequent lack of forensic sample will no longer be an obstacle. The need for a robust co-extraction method of DNA and total RNA is clear and there are several kits on the market to serve this need. This work aimed to establish an overview of nucleic acid extraction and dual extraction processes for body fluid identification as well as the use of commercial co-extraction kits.
Details
- Title
- Co-extraction methods of DNA and total RNA for body fluid identification: A review
- Authors/Creators
- Anh Tran
- Contributors
- Brendan Chapman (Supervisor)
- Awarding Institution
- Murdoch University; Masters by Coursework
- Identifiers
- 991005543261607891
- Murdoch Affiliation
- School of Medical, Molecular and Forensic Sciences
- Language
- English
- Resource Type
- Thesis
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