Thesis
Effects of endotracheal intubation on ventilation in horses
Masters by Research, Murdoch University
2022
Abstract
Equine respiratory physiology might be influenced by endotracheal intubation. This study aimed to compare breathing pattern (BrP) and ventilation distribution in anaesthetised horses spontaneously breathing room air via facemask (MASK) or endotracheal tube (ETT).
Electrical impedance tomography (EIT) via a thoracic belt was used in six horses anaesthetised with TIVA (xylazine, ketamine, guaiphenesin). Horses positioned in right lateral recumbency were randomly assigned to breathe spontaneously via one of the treatments (either ETT or MASK) for the first 30 minutes, followed by the other treatment for additional 30 minutes. During a second anaesthesia one month later treatment order was inversed. EIT data were collected over 2 minutes every 15 minutes. EIT impedance (ΔZ) curve was used to classify breaths as normal (linear inspiration and expiration), abnormal - sigh (>1.3 x ΔZ normal breath) and abnormal – crown-like (group of breaths with incomplete expiration in-between) (Figure 1). Ventral-dorsal (CoVVD) and right-left centre of ventilation (CoVRL), inspiratory (ti) and expiratory (te) times and I:E ratio were compared across treatments.
Breathing pattern was associated with treatment (p=0.0103) with more abnormal breaths during ETT (Cochran-Mantel-Haenszel analysis). COVVD was not different, but CoVRL showed more dependent ventilation during MASK (p = 0.041). Inspiratory time was shorter for ETT (p = 0.045) with lower I:E ratio (p = 0.003) (Mixed linear model analysis).
Endotracheal intubation alters BrP and shifts ventilation towards the non-dependent lung in horses anaesthetised with TIVA.
Details
- Title
- Effects of endotracheal intubation on ventilation in horses
- Authors/Creators
- Fernando Moreno Martinez
- Contributors
- Martina Mosing (Supervisor) - Murdoch University, Centre for Sustainable Aquatic Ecosystems
- Awarding Institution
- Murdoch University; Masters by Research
- Identifiers
- 991005548668807891
- Murdoch Affiliation
- School of Veterinary Medicine
- Resource Type
- Thesis
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