Journal article
A clonal complex 12 methicillin-resistant Staphylococcus aureus strain, West Australian MRSA-59, harbors a novel pseudo-SCCmec element
Antimicrobial agents and chemotherapy, Vol.59(11), pp.7142-7144
2015
Abstract
A West Australian methicillin-resistant Staphylococcus aureus strain (WA MRSA-59) was characterized by microarray and sequencing. Its pseudo-staphylococcal cassette chromosome mec (SCCmec) element comprised dcs, Q9XB68-dcs, mvaS-SCC, Q5HJW6, dru, ugpQ, ydeM, mecA-mecR-mecI, txbi mecI, tnp IS431, copA2-mco (copper resistance), ydhK, arsC-arsB-arsR (arsenic resistance), open reading frame PT43, and per-2. Recombinase genes, xylR (mecR2), and PSM-mec (phenol-soluble modulin) were absent. We suggest that mec complex A should be split into two subtypes. One harbors PSM-mec and xylR (mecR2). It is found in SCCmec types II, III, and VIII. The second subtype, described herein, is present in WA MRSA-59 and some coagulasenegative staphylococci.
Details
- Title
- A clonal complex 12 methicillin-resistant Staphylococcus aureus strain, West Australian MRSA-59, harbors a novel pseudo-SCCmec element
- Authors/Creators
- S. Monecke (Author/Creator)G.W. Coombs (Author/Creator)J. Pearson (Author/Creator)H. Hotzel (Author/Creator)P. Slickers (Author/Creator)R. Ehricht (Author/Creator)
- Publication Details
- Antimicrobial agents and chemotherapy, Vol.59(11), pp.7142-7144
- Publisher
- American Society for Microbiology
- Identifiers
- 991005540680707891
- Copyright
- © 2015, American Society for Microbiology.
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
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- Citation topics
- 1 Clinical & Life Sciences
- 1.23 Antibiotics & Antimicrobials
- 1.23.173 MRSA and VRE
- Web Of Science research areas
- Microbiology
- Pharmacology & Pharmacy
- ESI research areas
- Pharmacology & Toxicology