Journal article
A comparison of estimation methods for computational fluid dynamics outflow boundary conditions using patient-specific carotid artery
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, Vol.227(6), pp.663-671
2013
Abstract
Computational fluid dynamics simulations can provide important hemodynamic insights for investigating the effectiveness of carotid artery stenting, but its accuracy is dependent on the boundary conditions such as the outflow pressure, which is difficult to obtain by measurements. Many computational fluid dynamics simulations assume that the outflow pressure is constant (P = 0), but this method is likely to produce different results compared to clinical measurements. We have developed an alternative estimation method called the minimum energy loss method based on the concept of energy loss minimization at flow bifurcation. This new method has been tested on computational fluid dynamics simulation of two patients treated with carotid artery stenting, and its flow ratio at internal carotid artery and wall shear stress distribution was compared with the constant zero outlet pressure method. Three different procedure stages (prestent, poststent, and follow-up) were analyzed. The internal carotid artery flow ratio using the minimum energy loss method generally matched well with ultrasound measurements, but the internal carotid artery flow ratio based on zero outlet pressure method showed a large difference. Wall shear stress distributions varied between methods in response to the change in internal carotid artery flow rate. This study demonstrates the importance of accurate outlet boundary condition for assessing the long-term efficacy of carotid artery stenting and the risk of restenosis in treated patients.
Details
- Title
- A comparison of estimation methods for computational fluid dynamics outflow boundary conditions using patient-specific carotid artery
- Authors/Creators
- C-J Lee (Author/Creator) - Australian School of Advanced MedicineN. Uemiya (Author/Creator) - Saitama Medical UniversityS. Ishihara (Author/Creator) - Saitama Medical UniversityY. Zhang (Author/Creator) - Australian School of Advanced MedicineY. Qian (Author/Creator) - Australian School of Advanced Medicine
- Publication Details
- Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine, Vol.227(6), pp.663-671
- Publisher
- SAGE Publications
- Identifiers
- 991005542144107891
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.105 Strokes
- 1.105.1645 Wall Shear Stress
- Web Of Science research areas
- Engineering, Biomedical
- ESI research areas
- Engineering