Journal article
A low-spin iron complex in human melanoma and rat hepatoma cells and a high-spin iron(II) complex in rat hepatoma cells
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol.1135(2), pp.154-158
1992
Abstract
Human melanoma and rat hepatoma cells cultured in the presence of low concentrations (2.5 μM) of low-molecular-weight iron (Fe) chelates and Fe-transferrin complexes have been studied with 57Fe Mössbauer spectroscopy. The spectra show that holoferritin is only a minor fraction of the total iron present in the cells. The major form of Fe was in a low-spin state unlike the high-spin Fe(III) found in ferritin. Only about 10% of the Fe could be attributed to ferritin. In addition, the hepatoma cells had a high-spin Fe(II) spectral component which made up about 20% of the Fe present.
Details
- Title
- A low-spin iron complex in human melanoma and rat hepatoma cells and a high-spin iron(II) complex in rat hepatoma cells
- Authors/Creators
- T.G. St Pierre (Author/Creator)D.R. Richardson (Author/Creator) - The University of Western AustraliaE. Baker (Author/Creator) - School of Anatomy, Physiology and Human BiologyJ. Webb (Author/Creator) - Murdoch University
- Publication Details
- Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, Vol.1135(2), pp.154-158
- Publisher
- Elsevier B.V.
- Identifiers
- 991005542563607891
- Copyright
- © 1992 Elsevier Science Publishers B.V.
- Murdoch Affiliation
- School of Mathematical and Physical Sciences
- Language
- English
- Resource Type
- Journal article
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