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A review of major histocompatibility complex-disease associations in man and dog
Journal article   Peer reviewed

A review of major histocompatibility complex-disease associations in man and dog

M.J. Day and W.J. Penhale
Veterinary Research Communications, Vol.11(2), pp.119-132
1987
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Abstract

The organization and biology of the Major Histocompatibility Complexes (MHC) of man (HLA) and dog (DLA) are reviewed, and a summary is presented of laboratory techniques used to define allotypes. The nomenclature of this field and the mechanisms of disease association with the MHC are discussed. Currently recognized HLA-disease associations are enumerated, with emphasis on the value of the complement C4 marker. DLA-disease association studies into autoimmune disease, allergy and neoplasia are reviewed.

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Citation topics
1 Clinical & Life Sciences
1.6 Immunology
1.6.607 MHC Diversity
Web Of Science research areas
Veterinary Sciences
ESI research areas
Plant & Animal Science
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