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A simple method for monitoring chromatography column eluates for laccase activity during enzyme purification
Journal article   Peer reviewed

A simple method for monitoring chromatography column eluates for laccase activity during enzyme purification

R.F.H. Dekker, K.Y. Ling and A.M. Barbosa
Biotechnology Letters, Vol.22(2), pp.105-108
2000
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Abstract

A simple and economical method is described that allows rapid detection of laccase activity in chromatography column fractions during enzyme purification. Aliquots of column eluants are applied to filter paper coated with 2,2'-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid) (ABTS) containing a numbered grid, and incubated at ambient temperature for 20 min. Indications of enzyme activity are simply observed by a colour change. This method avoids having to manually assay each fraction of a chromatographic run for enzyme activity.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.87 Paper & Wood Materials Science
3.87.946 Ligninolytic Enzymes
Web Of Science research areas
Biotechnology & Applied Microbiology
ESI research areas
Biology & Biochemistry
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