Journal article
Absence of canine oral papillomavirus DNA following prophylactic L1 particle-mediated immunotherapeutic delivery vaccination
Journal of General Virology, Vol.83(9), pp.2299-2301
2002
Abstract
In the canine oral papillomavirus (COPV) model, following wart regression, COPV DNA was detected by PCR at the challenge site. However, following particle-mediated immunotherapeutic delivery (PMID) of COPV L1 and subsequent challenge, no COPV DNA could be detected. These data support PMID of COPV L1 as a protective vaccine and suggest that PMID of L1 may induce virus clearance.
Details
- Title
- Absence of canine oral papillomavirus DNA following prophylactic L1 particle-mediated immunotherapeutic delivery vaccination
- Authors/Creators
- R.A. Moore (Author/Creator) - University of CambridgeP.K. Nicholls (Author/Creator) - University of CambridgeE.B. Santos (Author/Creator) - University of CambridgeG.W. Gough (Author/Creator) - Glaxo Smithkline Research and Development, Medicines Research Centre, Stevenage, Hertfordshire SG1 2NY, UK2M.A. Stanley (Author/Creator) - University of Cambridge
- Publication Details
- Journal of General Virology, Vol.83(9), pp.2299-2301
- Publisher
- Society for General Microbiology
- Identifiers
- 991005542307707891
- Copyright
- © Society for General Microbiology
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Industry collaboration
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.179 Oncology
- 1.179.108 HPV and Cervical Cancer
- Web Of Science research areas
- Biotechnology & Applied Microbiology
- Virology
- ESI research areas
- Microbiology