Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection

U.I. Osuagwuh; V. Bagla; E.H. Venter; C.H. Annandale; P.C. Irons

doi:10.1016/j.vaccine.2006.12.010

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Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection

Journal article

Peer reviewed

Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection

U.I. Osuagwuh, V. Bagla, E.H. Venter, C.H. Annandale and P.C. Irons

Vaccine, Vol.25(12), pp.2238-2243

2007

DOI: https://doi.org/10.1016/j.vaccine.2006.12.010

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Abstract

Twelve serologically negative bulls were used, six were vaccinated with a modified live LSD vaccine and six unvaccinated. All were then experimentally infected with a virulent field strain of LSDV. No clinical abnormality was detected following vaccination, and mild clinical signs were seen in four vaccinated bulls following challenge. Virus was not found in semen of vaccinated bulls. Two of the unvaccinated bulls developed severe LSD and four showed mild symptoms, all excreted the virus in the semen following challenge. This study confirmed the ability of LSD vaccination to prevent the excretion of LSDV in semen of vaccinated bulls.

Details

Title: Absence of lumpy skin disease virus in semen of vaccinated bulls following vaccination and subsequent experimental infection
Authors/Creators: U.I. Osuagwuh (Author/Creator) - Onderstepoort Veterinary Academic Hospital
V. Bagla (Author/Creator) - University of Pretoria
E.H. Venter (Author/Creator) - University of Pretoria
C.H. Annandale (Author/Creator) - Onderstepoort Veterinary Academic Hospital
P.C. Irons (Author/Creator) - Onderstepoort Veterinary Academic Hospital
Publication Details: Vaccine, Vol.25(12), pp.2238-2243
Publisher: Elsevier BV
Identifiers: 991005544061007891
Copyright: © 2006 Elsevier Ltd.
Murdoch Affiliation: Murdoch University
Language: English
Resource Type: Journal article

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Citation topics: 1 Clinical & Life Sciences; 1.161 Virology - Identification & Sequencing; 1.161.1662 Poxvirus Immunology
Web Of Science research areas: Immunology; Medicine, Research & Experimental
ESI research areas: Immunology