Journal article
Accidental alfaxalone overdose in a mature cat undergoing anaesthesia for magnetic resonance imaging
JFMS open reports, Vol.2(1), pp.1-6
2016
PMCID: PMC5362862
PMID: 28491424
Abstract
This case report describes the clinical signs and treatment of an alfaxalone 10 times overdose in a 12-year-old cat undergoing anaesthesia for MRI. The cat was discharged from hospital following a prolonged recovery including obtunded mentation and cardiorespiratory depression for several hours following cessation of anaesthesia. The cat received supportive therapy that included supplemental oxygen via a face mask, intravenous crystalloid fluids and active rewarming. The benefits of using alfaxalone for maintenance of anaesthesia, its pharmacokinetics and previously reported lethal doses are discussed. Strategies for reducing the incidence of medication errors are presented. Relevance and novel information An unintentional overdose of alfaxalone by continuous rate infusion has not been reported previously in a cat. Treatment is supportive and directed towards maintenance of the cardiorespiratory systems. Whenever possible, smart pumps that have been designed to reduce human error should be used to help prevent medication errors associated with continuous rate infusions.
Details
- Title
- Accidental alfaxalone overdose in a mature cat undergoing anaesthesia for magnetic resonance imaging
- Authors/Creators
- Wendy Bayldon - The University of MelbourneJennifer E Carter - The University of MelbourneThierry Beths - The University of MelbourneLeon N Warne - The University of MelbourneTed Whittem - The University of MelbourneLorena Martinez - The University of MelbourneSébastien H Bauquier - The University of Melbourne
- Publication Details
- JFMS open reports, Vol.2(1), pp.1-6
- Publisher
- SAGE Publications
- Number of pages
- 6
- Identifiers
- 991005618221007891
- Copyright
- © The Author(s) 2016
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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