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CC BY V4.0, Open Access
Journal article
Accuracy of volume measurements by a clinical spirometer in multiple veterinary hospitals
Frontiers in veterinary science, Vol.11, 1475401
2024
PMID: 39698312
Abstract
Introduction: Spirometry devices, which are components of many anaesthesia machines, are commonly used to assess lung mechanics during anaesthesia. Spirometry calibration usually adheres to manufacturer recommendations without established guidelines. Although more accurate and less variable than inbuilt spirometry in certain General Electric anaesthesia ventilators, near-patient spirometry lacks adequate evaluation.
Methods: We assessed near-patient spirometers’ performance using Pedi-lite and D-lite flow sensors. Certified 1 L calibration syringes were used on 67 monitors located in 14 veterinary hospitals. Three consecutive inspired and expired volume values displayed by the monitors for each volume of the calibration syringe were recorded. Volumes studied were 50, 100, 150, 250, 300 mL for Pedi-lite and 150, 300, 450, 500, 750 mL for D-lite. Measured and targeted volumes were averaged, agreement error calculated. Accuracy was assessed plotting agreement errors against calibration volumes. A linear mixed-effects model was used to obtain linear regression between the error and the calibration volume. Mean, differential and proportional bias, limits of agreement, claimed accuracy and 10% clinical tolerance were calculated and displayed. Differences among monitors were evaluated using the Friedman rank sum test, differences between inspired and expired volumes using the Wilcoxon signed-rank.
Results: Inter-monitor variability for inspired and expired volume readings using both sensors was high; intra-monitor variability was low. The error magnitude was independent of volumes evaluated. Using Pedi-lite, only a minority of measurements met manufacturer’s specification or a 10% clinical tolerance; both inspired and expired volumes were significantly underestimated. Using D-lite, superior performance was demonstrated for volumes between 300 and 750 mL (mean biases close to zero and the majority of measurements meeting manufacturer’s specifications and clinical tolerance). The difference between measured inspired and expired volumes with both sensors was significant.
Discussion: These results support caution when interpreting clinical measurements of lung volumes and mechanics in anaesthetised patients when using these sensors. This is particularly important in smaller patients where lung volumes are below 300 mL. Trends should be reliable.
Details
- Title
- Accuracy of volume measurements by a clinical spirometer in multiple veterinary hospitals
- Authors/Creators
- Mathieu Raillard - Murdoch Univ, Coll Environm & Life Sci, Sch Vet Med, Murdoch, WA, AustraliaMartina Mosing - Murdoch University, Centre for Sustainable Aquatic EcosystemsAnthea Raisis - Murdoch Univ, Coll Environm & Life Sci, Sch Vet Med, Murdoch, WA, AustraliaAdam Auckburally - Southern Cty Vet Specialists, Ringwood, EnglandKarla Borland - Anderson Moores Vet Specialists, Hursley, EnglandSusana Canfran - Univ Complutense Madrid, Hosp Clin Vet Complutense, Madrid, SpainFrances Downing - Davies Vet Specialists, Shillington, Herts, EnglandAlejandra Garcia de Carellan Mateo - Hosp Vet Univ Catolica Valencia San Vicente Martir, Valencia, SpainPaul Macfarlane - University of BristolWilliam Mcfadzean - Cave Vet Specialists, Wellington, EnglandTristan Merlin - Eastcott Vet Clin & Hosp, Swindon, EnglandKarine Portier - VetAgro SupJosephine Robertson - University of GlasgowJoao Henrique Neves Soares - Univ Calif Davis, Sch Vet Med, Dept Surg & Radiol Sci, Davis, CA USABarbara Steblaj - University of ZurichAurora Zoff - North Downs Specialist Referrals, Bletchingley, EnglandOlivier L. Levionnois - University of Bern
- Publication Details
- Frontiers in veterinary science, Vol.11, 1475401
- Publisher
- Frontiers Media S.A.
- Number of pages
- 11
- Grant note
- Australian Government Research Training Program Scholarship; Australian Government; Department of Industry, Innovation and Science Catherine Heather Paton Bequest
- Identifiers
- 991005726580107891
- Copyright
- © 2024 Raillard et al.
- Murdoch Affiliation
- School of Veterinary Medicine
- Language
- English
- Resource Type
- Journal article
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