Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog

N.J. Russell; P.J. Irwin; B.J. Hopper; T. Olivry; P.K. Nicholls

doi:10.1111/j.1748-5827.2008.00253.x

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Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog

Journal article

Open access

Peer reviewed

Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog

N.J. Russell, P.J. Irwin, B.J. Hopper, T. Olivry and P.K. Nicholls

Journal of Small Animal Practice, Vol.49(7), pp.349-355

2008

DOI: https://doi.org/10.1111/j.1748-5827.2008.00253.x

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Abstract

A five-month-old female Jack Russell terrier was presented for investigation of acute lethargy, anorexia, coughing, respiratory distress and weakness. Examination findings included cyanosis, a grade 3 of 6 systolic heart murmur and prolonged capillary refill time. Radiography and echocardiography revealed severe pulmonary hypertension, cor pulmonale and right-sided heart failure. Indirect measurement of the systolic pulmonary artery pressure estimated pressures over 100 mmHg. Despite treatment the patient died. Postmortem examination did not identify a congenital cardiovascular anomaly. Histopathology confirmed acute necrotising pulmonary arteritis and immunohistochemistry failed to identify any immune complex or complement deposition.

Details

Title: Acute necrotising pulmonary vasculitis and pulmonary hypertension in a juvenile dog
Authors/Creators: N.J. Russell (Author/Creator) - Murdoch University
P.J. Irwin (Author/Creator) - Murdoch University
B.J. Hopper (Author/Creator) - Murdoch University
T. Olivry (Author/Creator) - North Carolina State University
P.K. Nicholls (Author/Creator) - Murdoch University
Publication Details: Journal of Small Animal Practice, Vol.49(7), pp.349-355
Publisher: Blackwell Publishing
Identifiers: 991005542938107891
Copyright: © 2008 British Small Animal Veterinary Association.
Murdoch Affiliation: School of Veterinary and Biomedical Sciences
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.37 Cardiology - General; 1.37.691 Pulmonary Hypertension
Web Of Science research areas: Veterinary Sciences
ESI research areas: Plant & Animal Science