Journal article
Adherence to a Mediterranean diet and Alzheimer’s disease risk in an Australian population
Translational Psychiatry, Vol.2(10), e164
2012
Abstract
The Mediterranean diet (MeDi), due to its correlation with a low morbidity and mortality for many chronic diseases, has been widely recognised as a healthy eating model. We aimed to investigate, in a cross-sectional study, the association between adherence to a MeDi and risk for Alzheimer’s disease (AD) and mild cognitive impairment (MCI) in a large, elderly, Australian cohort. Subjects in the Australian Imaging, Biomarkers and Lifestyle Study of Ageing cohort (723 healthy controls (HC), 98 MCI and 149 AD participants) completed the Cancer Council of Victoria Food Frequency Questionnaire. Adherence to the MeDi (0- to 9-point scale with higher scores indicating higher adherence) was the main predictor of AD and MCI status in multinominal logistic regression models that were adjusted for cohort age, sex, country of birth, education, apolipoprotein E genotype, total caloric intake, current smoking status, body mass index, history of diabetes, hypertension, angina, heart attack and stroke. There was a significant difference in adherence to the MeDi between HC and AD subjects (P<0.001), and in adherence between HC and MCI subjects (P<0.05). MeDi is associated with change in Mini-Mental State Examination score over an 18-month time period (P<0.05) in HCs. We conclude that in this Australian cohort, AD and MCI participants had a lower adherence to the MeDi than HC participants.
Details
- Title
- Adherence to a Mediterranean diet and Alzheimer’s disease risk in an Australian population
- Authors/Creators
- S. Gardener (Author/Creator) - Edith Cowan UniversityY. Gu (Author/Creator) - Columbia UniversityS.R. Rainey-Smith (Author/Creator)J.B. Keogh (Author/Creator) - University of South AustraliaP.M. Clifton (Author/Creator) - The University of AdelaideS.L. Mathieson (Author/Creator) - Hollywood Private HospitalK. Taddei (Author/Creator) - Edith Cowan UniversityA. Mondal (Author/Creator) - Edith Cowan UniversityV.K. Ward (Author/Creator) - Edith Cowan UniversityN. Scarmeas (Author/Creator) - Columbia UniversityM. Barnes (Author/Creator) - Preventative HealthK.A. Ellis (Author/Creator) - Mental Health Research InstituteR. Head (Author/Creator) - Preventative HealthC.L. Masters (Author/Creator) - Mental Health Research InstituteD. Ames (Author/Creator) - The University of MelbourneS.L. Macaulay (Author/Creator) - Preventative HealthC.C. Rowe (Author/Creator) - Austin HealthC. Szoeke (Author/Creator) - Preventative HealthR.N. Martins (Author/Creator) - Edith Cowan University
- Publication Details
- Translational Psychiatry, Vol.2(10), e164
- Publisher
- Macmillan Publishers Limited
- Identifiers
- 991005541571007891
- Copyright
- © 2012 Macmillan Publishers Limited
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.52 Neurodegenerative Diseases
- 1.52.60 Dementia
- Web Of Science research areas
- Psychiatry
- ESI research areas
- Psychiatry/Psychology