Journal article
Adjuvant efficacy of G2 (buffalo spleen extraction) against Yersinia septicemia in rainbow trout (Onchorhynchus mykiss)
Fish & Shellfish Immunology, Vol.82, pp.115-120
2018
Abstract
Adjuvant effect of G2 (extraction of buffalo spleen) was assessed in intraperitoneally immunized rainbow trout (100–150 g) with killed- Y. ruckeri bacterin biotype I [0.1 mL (1 × 107 cells/fish) of vaccine diluted with the adjuvant in a ratio of 1:1 (V/V)] at 12.4 ± 1.3 °C for 10 weeks. Leukocyte and lymphocyte counts, anti-Y. ruckeri antibody titer and relative percent survival (RPS) in fish vaccinated with vaccine containing the adjuvant were significantly higher than the immunized fish with Y. ruckeri antigen alone throughout the experiment (P < 0.05), but neutrophils count and lysozyme activity were mostly significantly higher in the latter group (P < 0.05). No difference was seen in the complement activity between vaccinated fish containing the adjuvant and vaccine alone (P > 0.05). The results of this work for the first time demonstrated that inclusion of G2 as an adjuvant in Y. urckeri vaccine can improve the efficacy of the vaccine against Yersinia septicemia in rainbow trout.
Details
- Title
- Adjuvant efficacy of G2 (buffalo spleen extraction) against Yersinia septicemia in rainbow trout (Onchorhynchus mykiss)
- Authors/Creators
- S. Shafiei (Author/Creator)E. Soltani (Author/Creator)M. Soltani (Author/Creator)S.M. Hazrati (Author/Creator)
- Publication Details
- Fish & Shellfish Immunology, Vol.82, pp.115-120
- Publisher
- Elsevier Ltd
- Identifiers
- 991005542402407891
- Copyright
- © 2018 Published by Elsevier Ltd.
- Murdoch Affiliation
- School of Veterinary and Life Sciences; Freshwater Fish Group and Fish Health Unit
- Language
- English
- Resource Type
- Journal article
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- Domestic collaboration
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- Citation topics
- 1 Clinical & Life Sciences
- 1.42 Bacteriology
- 1.42.853 Aquatic Pathogens
- Web Of Science research areas
- Fisheries
- Immunology
- Marine & Freshwater Biology
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science