Journal article
Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study
Internal Medicine Journal, Vol.47(11), pp.1306-1310
2017
Abstract
In this study, linked Western Australian health data were used to determine presence of an antibiotic-resistant infection (ABRI) for all people diagnosed with a primary invasive cancer in 2009. Of 10 858 cancer cases, 154 (1.42%) had an ABRI. Patients with an ABRI were older (71.5 vs 66 years), and more had died in the year following diagnosis (37.7 vs 20.2%, P < 0.001). The ABRI cohort had a higher proportion of colorectal, genitourinary and haematological cancers (19.5 vs 11.9%; 14.3 vs 9.7% and 16.9 vs 5.8%, respectively). Hospital admissions with an ABRI were longer (22.3 vs 2.9 days, P < 0.001) and had a higher proportion of unplanned admissions (60.3 vs 15.2%), admissions through emergency department (36.8 vs 8.3%) and intensive care admissions (14.9 vs 1.7%, P < 0.001). Patients with solid tumours who developed an ABRI were more likely to have received chemotherapy (35.9 vs 27.8%, P = 0.04). In haematological cancer patients, a greater proportion of the admissions with an ABRI occurred after radiation therapy or chemotherapy (P = 0.01 and P = 0.005, respectively). This study is the first to report population-level data on ABRI in cancer patients. Patients with an ABRI had more hospital admissions and poorer outcomes.
Details
- Title
- Admissions for antibiotic-resistant infections in cancer patients during first year of cancer diagnosis: a cross-sectional study
- Authors/Creators
- N. Slavova-Azmanova (Author/Creator) - The University of Western AustraliaL. Haddow (Author/Creator) - The University of Western AustraliaH. Hohnen (Author/Creator) - The University of Western AustraliaG.W. Coombs (Author/Creator) - Fiona Stanley HospitalJ.O. Robinson (Author/Creator) - Royal Perth HospitalA. Ives (Author/Creator) - The University of Western Australia
- Publication Details
- Internal Medicine Journal, Vol.47(11), pp.1306-1310
- Publisher
- Blackwell Publishing
- Identifiers
- 991005540008207891
- Copyright
- © 2017 Royal Australasian College of Physicians
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.23 Antibiotics & Antimicrobials
- 1.23.146 Antimicrobial Resistance
- Web Of Science research areas
- Infectious Diseases
- ESI research areas
- Clinical Medicine