Journal article
Albendazole: a more effective antigiardial agent in vitro than metronidazole or tinidazole
Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol.84(3), pp.375-379
1990
Abstract
The effects of albendazole were assessed against Giardia duodenalis in vitro and compared with those of tinidazole and metronidazole. Trophozoite morphology, adherence and viability were markedly affected by albendazole, to a far greater extent than by either metronidazole or tinidazole. The results of this study, and in particular the superior potency of albendazole in vitro, are discussed with respect to its potential value as a new approach to the chemotherapy of giardiasis.
Details
- Title
- Albendazole: a more effective antigiardial agent in vitro than metronidazole or tinidazole
- Authors/Creators
- B.P. Meloni (Author/Creator) - Murdoch UniversityR.C.A. Thompson (Author/Creator)J.A. Reynoldson (Author/Creator) - Murdoch UniversityP. Seville (Author/Creator) - Smith, Kline & French
- Publication Details
- Transactions of the Royal Society of Tropical Medicine and Hygiene, Vol.84(3), pp.375-379
- Publisher
- Royal Society of Tropical Medicine and Hygiene
- Identifiers
- 991005545992707891
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Citation topics
- 1 Clinical & Life Sciences
- 1.246 Diarrheal Diseases
- 1.246.985 Cryptosporidium
- Web Of Science research areas
- Public, Environmental & Occupational Health
- Tropical Medicine
- ESI research areas
- Social Sciences, general