Journal article
American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines: Small animal
Journal of Veterinary Emergency and Critical Care, Vol.29(1), pp.12-36
2019
Abstract
Objectives
To systematically review available evidence and establish guidelines related to the risk of developing thrombosis and the management of small animals with antithrombotics.
Design
Standardized, systematic evaluation of the literature (identified by searching Medline via PubMed and CAB abstracts) was carried out in 5 domains (Defining populations at risk; Defining rational therapeutic use; Defining evidence‐based protocols; Refining and monitoring antithrombotic therapies; and Discontinuing antithrombotic therapies). Evidence evaluation was carried out using Population, Intervention, Comparison, Outcome generated within each domain questions to address specific aims. This was followed by categorization of relevant articles according to level of evidence and quality (Good, Fair, or Poor). Synthesis of these data led to the development of a series of statements. Consensus on the final guidelines was achieved via Delphi‐style surveys. Draft recommendations were presented at 2 international veterinary conferences and made available for community assessment, review, and comment prior to final revisions and publication.
Settings
Academic and referral veterinary medical centers.
Results
Over 500 studies were reviewed in detail. Worksheets from all 5 domains generated 59 statements with 83 guideline recommendations that were refined during 3 rounds of Delphi surveys. A high degree of consensus was reached across all guideline recommendations.
Conclusions
Overall, systematic evidence evaluations yielded more than 80 recommendations for the treatment of small animals with or at risk of developing thrombosis. Numerous significant knowledge gaps were highlighted by the evidence reviews undertaken, indicating the need for substantial additional research in this field.
Details
- Title
- American College of Veterinary Emergency and Critical Care (ACVECC) Consensus on the Rational Use of Antithrombotics in Veterinary Critical Care (CURATIVE) guidelines: Small animal
- Authors/Creators
- R. Goggs (Author/Creator)M-C Blais (Author/Creator)B.M. Brainard (Author/Creator)D.L. Chan (Author/Creator)A.M. de Laforcade (Author/Creator)E. Rozanski (Author/Creator)C.R. Sharp (Author/Creator)
- Publication Details
- Journal of Veterinary Emergency and Critical Care, Vol.29(1), pp.12-36
- Publisher
- Wiley
- Identifiers
- 991005541747907891
- Copyright
- © Veterinary Emergency and Critical Care Society 2019
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.232 Veterinary Sciences
- 3.232.1281 Veterinary Reproductive Health
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science