Amygdala volumetric change following psychotherapy for posttraumatic stress disorder

J. Laugharne; C. Kullack; C.W. Lee; T.M. McGuire; S. Brockman; P.D. Drummond; S. Starkstein

doi:10.1176/appi.neuropsych.16010006

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Amygdala volumetric change following psychotherapy for posttraumatic stress disorder

Journal article

Peer reviewed

Amygdala volumetric change following psychotherapy for posttraumatic stress disorder

J. Laugharne, C. Kullack, C.W. Lee, T.M. McGuire, S. Brockman, P.D. Drummond and S. Starkstein

The Journal of Neuropsychiatry and Clinical Neurosciences, Vol.28(4), pp.312-318

2016

DOI: https://doi.org/10.1176/appi.neuropsych.16010006

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Abstract

The authors investigated the impact of eye movement desensitization and reprocessing (EMDR) and prolonged exposure (PE) on the volumes of the amygdala and hippocampus, structures known to be important in fear conditioning, in 20 patients with posttraumatic stress disorder (PTSD). Patients were randomly allocated to either EMDR or PE. Volumes were assessed before and after treatment via magnetic resonance imaging (MRI). Both groups showed significant improvements in PTSD symptoms. Left amygdala mean volume increased significantly following EMDR treatment only. No significant volumetric changes were found for the hippocampus.

Details

Title: Amygdala volumetric change following psychotherapy for posttraumatic stress disorder
Authors/Creators: J. Laugharne (Author/Creator) - School of Psychiatry and Clinical Neurosciences
C. Kullack (Author/Creator) - School of Psychiatry and Clinical Neurosciences
C.W. Lee (Author/Creator) - Murdoch University
T.M. McGuire (Author/Creator) - Murdoch University
S. Brockman (Author/Creator) - School of Psychiatry and Clinical Neurosciences
P.D. Drummond (Author/Creator) - Murdoch University
S. Starkstein (Author/Creator) - School of Psychiatry and Clinical Neurosciences
Publication Details: The Journal of Neuropsychiatry and Clinical Neurosciences, Vol.28(4), pp.312-318
Publisher: American Psychiatric Publishing
Identifiers: 991005541553107891
Copyright: © 2016 American Psychiatric Association
Murdoch Affiliation: School of Psychology and Exercise Science
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration
Citation topics: 6 Social Sciences; 6.24 Psychiatry & Psychology; 6.24.93 Trauma and PTSD
Web Of Science research areas: Clinical Neurology; Neurosciences; Psychiatry
ESI research areas: Neuroscience & Behavior