An abattoir-based study on the prevalence of bovine tuberculosis from culled adult dairy cows in Wuhan, China

X. Zhu; Y. Yan; Z. Wang; K. Zhang; Y. Chen; Y. Peng; Q. Peng; A. Guo; I.D. Robertson; J. Aleri

doi:10.1016/j.prevetmed.2021.105477

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An abattoir-based study on the prevalence of bovine tuberculosis from culled adult dairy cows in Wuhan, China

Journal article

Peer reviewed

An abattoir-based study on the prevalence of bovine tuberculosis from culled adult dairy cows in Wuhan, China

X. Zhu, Y. Yan, Z. Wang, K. Zhang, Y. Chen, Y. Peng, Q. Peng, A. Guo, I.D. Robertson and J. Aleri

Preventive Veterinary Medicine, Vol.196, Article 105477

2021

DOI: https://doi.org/10.1016/j.prevetmed.2021.105477

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Abstract

Abattoir surveillance is an integral component of a bovine tuberculosis (bTB) eradication programme. The objective of this study was to determine the prevalence of bTB among culled adult dairy cows in Wuhan, China and to further assess two diagnostic procedures as an adjunct to the confirmation of M. bovis in animals with TB-like lesions. The study was conducted in an abattoir located in Wuhan, China over a period of 41 days from June to July 2019. A total of 171 culled adult dairy cows were sampled and inspected, and blood samples collected from 134 of these. The viscera and lymph nodes of the carcasses were visually inspected and palpated for TB-like lesions. A total of 28.1 % (48/171) of the carcasses had gross TB-like lesions. 89.6 % (43/48) of the animals with TB-like lesions were positive to a PCR procedure for bTB. The sensitivity and specificity for post-mortem examination for TB-like lesions using a Bayesian latent class analysis model was estimated to be 60.8 % and 86.6 %, respectively. A seroprevalence of 20.9 % (28/134) was recorded for antibody response to M. bovis antigens MPB70 and MPB83 based on an ELISA procedure. There was a low-moderate agreement between the ELISA and PCR results in the detection of bTB (Kappa = 0.46, 95 % CI: 0.24−0.67). The study confirms a high prevalence of bTB among culled adult dairy cows in the abattoir and highlights the need to implement surveillance for bTB based on post-mortem examination and ELISA and PCR methods in association with backward tracing of infected dairy herds.

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Title: An abattoir-based study on the prevalence of bovine tuberculosis from culled adult dairy cows in Wuhan, China
Authors/Creators: X. Zhu (Author/Creator) - Huazhong Agricultural University
Y. Yan (Author/Creator) - Huazhong Agricultural University
Z. Wang (Author/Creator) - Huazhong Agricultural University
K. Zhang (Author/Creator) - Huazhong Agricultural University
Y. Chen (Author/Creator) - Huazhong Agricultural University
Y. Peng (Author/Creator) - Huazhong Agricultural University
Q. Peng (Author/Creator) - Wuhan Keqian Biology Co. Ltd, Wuhan, Hubei 430070, China.
A. Guo (Author/Creator) - Huazhong Agricultural University
I.D. Robertson (Author/Creator) - Huazhong Agricultural University
J. Aleri (Author/Creator) - Murdoch University
Publication Details: Preventive Veterinary Medicine, Vol.196, Article 105477
Publisher: Elsevier
Identifiers: 991005544466207891
Copyright: © 2021 Elsevier B.V.
Murdoch Affiliation: School of Veterinary Medicine; Centre for Animal Production and Health; Food Futures Institute
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.194 Tuberculosis & Leprosy; 1.194.273 TB Diagnostics & Treatment
Web Of Science research areas: Veterinary Sciences
ESI research areas: Plant & Animal Science