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An exploratory study of changes in salivary cortisol, depression, and pain intensity after treatment for chronic pain
Journal article   Open access   Peer reviewed

An exploratory study of changes in salivary cortisol, depression, and pain intensity after treatment for chronic pain

K.D. Evans, W. Douglas, N. Bruce and P.D. Drummond
Pain Medicine, Vol.9(6), pp.752-758
2008
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Abstract

To investigate the relationship between cortisol levels, pain intensity, and negative mood in chronic pain patients participating in a multidisciplinary pain management program. Eighteen chronic pain patients collected saliva samples over several days both directly before and after attending a 4-week multidisciplinary pain management program. Saliva samples were assayed for their cortisol concentration. Participants also completed self-report measures of pain intensity and depression.Usual pain intensity and waking cortisol levels changed in parallel following treatment, as did changes in depression and cortisol levels late in the morning and in the evening. Depression did not mediate the association between cortisol and usual pain intensity; neither did pain intensity moderate the association between cortisol and depression. Changes in cortisol secretion may provide a useful biological marker of treatment outcome in chronic pain patients after their participation in a multidisciplinary pain management program.

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Collaboration types
Domestic collaboration
Citation topics
1 Clinical & Life Sciences
1.5 Neuroscience
1.5.420 Stress and Cortisol
Web Of Science research areas
Anesthesiology
ESI research areas
Clinical Medicine
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