Journal article
Antimicrobial susceptibility testing of Serpulina hyodysenteriae
Australian Veterinary Journal, Vol.71(7), pp.211-214
1994
Abstract
Summary The macrobroth dilution technique was used to test the in-vitro effectiveness of 4 commonly used antimicrobial agents against 23 Australian isolates and 7 overseas strains of Serpulina hyodysenteriae. Minimum inhibitory concentrations and minimum bactericidal concentrations were determined. The growth of 90% of isolates was inhibited by dimetridazole at a concentration of 4 μg/mL, and by tiamulin at 8 μg/mL Australian isolates resistant to both antimicrobial agents were identified. Lincomycin was less effective than these antimicrobial agents, with 90% of isolates requiring a concentration of 128 μg/mL for inhibition of growth, and 54% being susceptible at 64 μg/mL. Tylosin did not prevent the growth of the majority of S hyodysenteriae isolates tested, and 90% were resistant to concentrations of 128 μg/mL. Resistant isolates came from different geographical areas. Resistance was not related to overall genetic background of the spirochaetes, and was not correlated with the presence of plasmids or the serogroup of the isolates.
Details
- Title
- Antimicrobial susceptibility testing of Serpulina hyodysenteriae
- Authors/Creators
- N.B Buller (Author/Creator)D.J. Hampson (Author/Creator)
- Publication Details
- Australian Veterinary Journal, Vol.71(7), pp.211-214
- Publisher
- Wiley-Blackwell
- Identifiers
- 991005542344007891
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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