Journal article
Antiviral Drug Allergy
Immunology and Allergy Clinics of North America, Vol.34(3), pp.645-662
2014
Abstract
Antiviral drugs used to treat HIV and hepatitis C are common causes of delayed drug hypersensitivities for which many of the more severe reactions have been recently shown to be immunogenetically mediated such as abacavir hypersensitivity where HLA-B*57:01 is now used routinely as a screening test to exclude patients carrying this allele from abacavir prescription. Most antiviral drug allergies consist of mild to moderate delayed rash without other serious features (e.g. fever, mucosal involvement, blistering rash, organ impairment. In these cases treatment can be continued with careful observation and symptomatic management and the discontinuation rate is low.
Details
- Title
- Antiviral Drug Allergy
- Authors/Creators
- B. Milpied-Homsi (Author/Creator) - Hôpital Saint-AndréE.M. Moran (Author/Creator) - Murdoch UniversityE.J. Phillips (Author/Creator) - Murdoch University
- Publication Details
- Immunology and Allergy Clinics of North America, Vol.34(3), pp.645-662
- Publisher
- Elsevier
- Identifiers
- 991005544551207891
- Copyright
- © 2014 Elsevier Inc.
- Murdoch Affiliation
- Institute for Immunology and Infectious Diseases
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.265 Dermatology - Skin Allergies
- 1.265.1140 Drug Hypersensitivity
- Web Of Science research areas
- Allergy
- Immunology
- ESI research areas
- Immunology