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Approach to the synthesis of (+)-Ifforestine. Model studies directed at the tetracyclic framework
Journal article   Peer reviewed

Approach to the synthesis of (+)-Ifforestine. Model studies directed at the tetracyclic framework

G.H.P. Roos and K.A. Dastlik
Heterocycles, Vol.60(9), pp.2023-2044
2003
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Abstract

In order to design an effective asymmetric synthesis of (+)-ifforestine, model approaches to the construction of the tetracyclic ring system have been investigated. These studies have identified two key synthons, a functionalized isatoic anhydride and a pipecolic acid derivative, as suitable AB- and D-ring portions for creation of the crucial diazopinedione C-ring.

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