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Aromatic metabolism in Rhizobium trifolii - protocatechuate 3,4-dioxygenase
Journal article   Peer reviewed

Aromatic metabolism in Rhizobium trifolii - protocatechuate 3,4-dioxygenase

Y.P. Chen, M.J. Dilworth and A.R. Glenn
Archives of Microbiology, Vol.138(3), pp.187-190
1984
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Abstract

Protocatechuate 3,4-dioxygenase (EC 1.13.11.3) has been purified 42-fold from 4-hydroxybenzoate-grown cells of Rhizobium trifolii TA1, where it constitutes about 2% of the cell protein. The dioxygenase has a molecular weight of 220,000, with two dissimilar sub-units of molecular weights 29,000 and 26,500, corresponding to an α4β4 composition. The enzyme is specific for protocatechuate, with a Km of 1.75×10-5 M and maximum activity at pH 9.2. Metal removal and replacement studies indicate that the enzyme contains complexed Fe3+ which is required for activity. Direct atomic absorption analysis gave 1.3–1.5 g atoms Fe3+ per mole of isolated enzyme, but correction for metal-deficient proteins suggests that the value is close to 2.

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Citation topics
3 Agriculture, Environment & Ecology
3.83 Bioengineering
3.83.323 Bioremediation
Web Of Science research areas
Microbiology
ESI research areas
Microbiology
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