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Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits
Journal article   Peer reviewed

Association and expression analysis of porcine HNF1A gene related to meat and carcass quality traits

A. Kayan, M.J. Uddin, H. Kocamis, D. Tesfaye, C. Looft, E. Tholen, K. Schellander and M.U. Çınar
Meat Science, Vol.94(4), pp.474-479
2013
DOI: https://doi.org/10.1016/j.meatsci.2013.04.015
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Abstract

The aim of this study was to investigate the association and expression of HNF1A gene as a candidate gene for meat and carcass quality traits in pigs. Statistical analysis revealed that the g.8260 A>G polymorphism significantly associated with pH 24H, meat percentage and muscle area in the F2 Duroc × Pietrain (DuPi, n = 313) and with pH 24L, fat area and backfat thickness in the Pietrain (Pi, n = 110) population. HNF1A mRNA and protein expressions were higher (p < 0.05) in animals with the low post-mortem muscle pH 24L. The promoter methylation profiling suggested that methylation was not involved on HNF1A expression regulation (p > 0.05) in animal with divergent muscle pH. In conclusion, polymorphism in porcine HNF1A gene could be used as a candidate marker to improve the meat and carcass quality traits, with the consideration of breed-specific effect.

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Collaboration types
Domestic collaboration
International collaboration
Citation topics
3 Agriculture, Environment & Ecology
3.51 Dairy & Animal Sciences
3.51.206 Meat Quality
Web Of Science research areas
Food Science & Technology
ESI research areas
Agricultural Sciences
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