Journal article
Avian reovirus proteins associated with neutralization of virus infectivity
Virology, Vol.194(2), pp.688-696
1993
Abstract
Monoclonal antibodies against two virion proteins of the RAM-1 strain of avian reovirus neutralized virus infectivity; antibody against a 124-kDa(λB) protein caused broadly specific neutralization and antibody against a 39-kDa (σC) protein caused neutralization of greater type-specificity. The neutralizing activity of the monoclonals also exhibited host cell specificity: antibodies against the λB protein inhibited virus infectivity in Vero cells and not chicken kidney cells; one monoclonal antibody against the σC protein neutralized virus in only chicken kidney cells, whereas two other monoclonals against the σC protein neutralized virus in both Vero and chicken kidney cells but had greater neutralizing activity in Vero cells.
Details
- Title
- Avian reovirus proteins associated with neutralization of virus infectivity
- Authors/Creators
- R. Wickramasinghe (Author/Creator)J. Meanger (Author/Creator)C.E. Enriquez (Author/Creator)G.E. Wilcox (Author/Creator)
- Publication Details
- Virology, Vol.194(2), pp.688-696
- Publisher
- Elsevier
- Identifiers
- 991005543830707891
- Murdoch Affiliation
- School of Veterinary Studies
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.228 Virology - Tropical Diseases
- 1.228.1892 Arbovirus Dynamics
- Web Of Science research areas
- Virology
- ESI research areas
- Microbiology