Azathioprine therapy in a case of pediatric multiple sclerosis that was seropositive for MOG-IgG

Y. Zhou; Q. Huang; T. Lu; X. Sun; L. Fang; Z. Lu; X. Hu; A. Kermode; W. Qiu

doi:10.1016/j.jocn.2016.12.022

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Azathioprine therapy in a case of pediatric multiple sclerosis that was seropositive for MOG-IgG

Journal article

Peer reviewed

Azathioprine therapy in a case of pediatric multiple sclerosis that was seropositive for MOG-IgG

Y. Zhou, Q. Huang, T. Lu, X. Sun, L. Fang, Z. Lu, X. Hu, A. Kermode and W. Qiu

Journal of Clinical Neuroscience, Vol.38, pp.71-73

2017

DOI: https://doi.org/10.1016/j.jocn.2016.12.022

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Abstract

There is a lack of evidence for treatment of pediatric multiple sclerosis (PedMS). Treatment using azathioprine for PedMS has not been reported. A 10-year-old boy with multiple sclerosis who was seropositive for antibodies against myelin oligodendrocyte glycoprotein (MOG)-IgG was treated with azathioprine plus oral methylprednisolone. The patient showed clinical and magnetic resonance imaging stability, with MOG-IgG seroconversion. There were no major side effects over a 5-year period. Azathioprine may be a treatment option, particularly in poor medical resource areas, for pediatric patients with multiple sclerosis who are seropositive for MOG-IgG.

Details

Title: Azathioprine therapy in a case of pediatric multiple sclerosis that was seropositive for MOG-IgG
Authors/Creators: Y. Zhou (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
Q. Huang (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
T. Lu (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
X. Sun (Author/Creator)
L. Fang (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
Z. Lu (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
X. Hu (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
A. Kermode (Author/Creator) - The University of Western Australia
W. Qiu (Author/Creator) - Third Affiliated Hospital of Sun Yat-sen University
Publication Details: Journal of Clinical Neuroscience, Vol.38, pp.71-73
Publisher: Churchill Livingstone
Identifiers: 991005541775807891
Copyright: © 2017 Elsevier Ltd.
Murdoch Affiliation: Institute for Immunology and Infectious Diseases
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.203 Neuromuscular Disorders; 1.203.147 Multiple Sclerosis
Web Of Science research areas: Clinical Neurology; Neurosciences
ESI research areas: Neuroscience & Behavior