Journal article
BRUCE: a program for the detection of transfer-messenger RNA genes in nucleotide sequences
Nucleic Acids Research, Vol.30(15), pp.3449-3453
2002
Abstract
A computer program, BRUCE, was developed for the identification of transfer‐messenger RNA (tmRNA) genes. The program employs heuristic algorithms to search for a tRNAAla‐like secondary structure surrounding a short sequence encoding the tag peptide. In the 57 completely sequenced bacterial genomes where tmRNA genes have been reported previously, BRUCE identified all with no false positives. In addition, BRUCE found 99 of the 100 tmRNAs identified previously in other bacteria, red chloroplasts and cyanelles. The output of the program reports the proposed tRNA secondary structure, the tmRNA gene sequence and the tag peptide.
Details
- Title
- BRUCE: a program for the detection of transfer-messenger RNA genes in nucleotide sequences
- Authors/Creators
- D. Laslett (Author/Creator) - Murdoch UniversityB. Canback (Author/Creator)S. Andersson (Author/Creator)
- Publication Details
- Nucleic Acids Research, Vol.30(15), pp.3449-3453
- Publisher
- Oxford University Press
- Identifiers
- 991005543911507891
- Copyright
- © 2002 Oxford University Press
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 2 Chemistry
- 2.170 Nucleic Acids Chemistry
- 2.170.185 RNA Translation Dynamics
- Web Of Science research areas
- Biochemistry & Molecular Biology
- ESI research areas
- Biology & Biochemistry