Journal article
Biocompatibility of synthesised nano-porous anodic Aluminium oxide membranes for use as a cell culture substrate for Madin-Darby Canine Kidneys cells: A preliminary study
Journal of Tissue Science & Engineering, Vol.3(3)
2012
Abstract
In this study we investigate for the first time the biomedical potential of using a membrane made from anodic aluminium oxide (AAO) for culturing the Madin-Darby Canine Kidney (MDCK) epithelial cell line. Nano-porous aluminium oxide membranes exhibit interesting properties such as high porosity, which allows the exchange of molecules and nutrients across the membrane and can be made with highly specific pore sizes that can be preselected by adjusting the controlling parameters of a temperature controlled two-step anodization process. The cellular response and interactions of the MDCK cell line with the synthesised nano-porous AAO membrane, a commercially available membrane and a glass control were assessed by investigating cell adhesion, morphology and proliferation.
Details
- Title
- Biocompatibility of synthesised nano-porous anodic Aluminium oxide membranes for use as a cell culture substrate for Madin-Darby Canine Kidneys cells: A preliminary study
- Authors/Creators
- G.E.J. Poinern (Author/Creator)N. Ali (Author/Creator)C. Berry (Author/Creator)P. Singh (Author/Creator)S. Berchmans (Author/Creator)D. Fawcett (Author/Creator)
- Publication Details
- Journal of Tissue Science & Engineering, Vol.3(3)
- Publisher
- OMICS Publishing Group
- Identifiers
- 991005542021507891
- Copyright
- © 2012 Poinern GEJ, et al
- Murdoch Affiliation
- School of Engineering and Energy
- Language
- English
- Resource Type
- Journal article
- Note
- This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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