Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015 : findings from the Global Burden of Disease 2015 study

Ali H. Mokdad; Aliasghar Ahmad Kiadaliri; Khurshid Alam; GBD 2015 Eastern Mediterranean Region LRI Collaborators

doi:10.1007/s00038-017-1007-0

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Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015 : findings from the Global Burden of Disease 2015 study

Journal article

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Peer reviewed

Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015 : findings from the Global Burden of Disease 2015 study

Ali H. Mokdad, Aliasghar Ahmad Kiadaliri, Khurshid Alam and GBD 2015 Eastern Mediterranean Region LRI Collaborators

International journal of public health, Vol.63(S1), pp.97-108

2018

DOI: https://doi.org/10.1007/s00038-017-1007-0

PMCID: PMC5973986

PMID: 28776246

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Abstract

DALY

Eastern Mediterranean Region

Incidence

Lower respiratory infection

Mortality

Objectives: We used data from the Global Burden of Disease 2015 study (GBD) to calculate the burden of lower respiratory infections (LRIs) in the 22 countries of the Eastern Mediterranean Region (EMR) from 1990 to 2015. Methods: We conducted a systematic analysis of mortality and morbidity data for LRI and its specific etiologic factors, including pneumococcus, Haemophilus influenzae type b, Respiratory syncytial virus, and influenza virus. We used modeling methods to estimate incidence, deaths, and disability-adjusted life-years (DALYs). We calculated burden attributable to known risk factors for LRI. Results: In 2015, LRIs were the fourth-leading cause of DALYs, causing 11,098,243 (95% UI 9,857,095-12,396,566) DALYs and 191,114 (95% UI 170,934-210,705) deaths. The LRI DALY rates were higher than global estimates in 2015. The highest and lowest age-standardized rates of DALYs were observed in Somalia and Lebanon, respectively. Undernutrition in childhood and ambient particulate matter air pollution in the elderly were the main risk factors. Conclusions: Our findings call for public health strategies to reduce the level of risk factors in each age group, especially vulnerable child and elderly populations.

Details

Title: Burden of lower respiratory infections in the Eastern Mediterranean Region between 1990 and 2015 : findings from the Global Burden of Disease 2015 study
Authors/Creators: Ali H. Mokdad - Institute for Health Metrics and Evaluation
Aliasghar Ahmad Kiadaliri - Lund OsteoArthritis Division - Clinical Epidemiology Unit
Khurshid Alam - Centre for Healthy Ageing
GBD 2015 Eastern Mediterranean Region LRI Collaborators
Publication Details: International journal of public health, Vol.63(S1), pp.97-108
Identifiers: 991005591500107891
Murdoch Affiliation: Centre for Healthy Ageing
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.23 Infection Management & Resistance; 1.23.347 Streptococcus Pneumoniae
Web Of Science research areas: Public, Environmental & Occupational Health
ESI research areas: Social Sciences, general