Journal article
COVID-19: pathogenesis, advances in treatment and vaccine development and environmental impact—an updated review
Environmental Science and Pollution Research
2021
Abstract
Diseases negatively impact the environment, causing many health risks and the spread of pollution and hazards. A novel coronavirus, severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has led to a recent respiratory syndrome epidemic in humans. In December 2019, the sudden emergence of this new coronavirus and the subsequent severe disease it causes created a serious global health threat and hazards. This is in contrast to the two aforementioned coronaviruses, SARS-CoV-2 (in 2002) and middle east respiratory syndrome coronavirus MERS-CoV (in 2012), which were much more easily contained. The World Health Organization (WHO) dubbed this contagious respiratory disease an “epidemic outbreak” in March 2020. More than 80 companies and research institutions worldwide are working together, in cooperation with many governmental agencies, to develop an effective vaccine. To date, six authorized vaccines have been registered. Up till now, no approved drugs and drug scientists are racing from development to clinical trials to find new drugs for COVID-19. Wild animals, such as snakes, bats, and pangolins are the main sources of coronaviruses, as determined by the sequence homology between MERS-CoV and viruses in these animals. Human infection is caused by inhalation of respiratory droplets. To date, the only available treatment protocol for COVID-19 is based on the prevalent clinical signs. This review aims to summarize the current information regarding the origin, evolution, genomic organization, epidemiology, and molecular and cellular characteristics of SARS-CoV-2 as well as the diagnostic and treatment approaches for COVID-19 and its impact on global health, environment, and economy.
Details
- Title
- COVID-19: pathogenesis, advances in treatment and vaccine development and environmental impact—an updated review
- Authors/Creators
- Y.A. Attia (Author/Creator) - Damanhour UniversityM.T. El-Saadony (Author/Creator)A.A. Swelum (Author/Creator)S.Y.A. Qattan (Author/Creator) - King Abdulaziz UniversityA.D. Al-qurashi (Author/Creator) - King Abdulaziz UniversityK.A. Asiry (Author/Creator) - King Abdulaziz UniversityM.E. Shafi (Author/Creator) - King Abdulaziz UniversityA.R. Elbestawy (Author/Creator) - Damanhour UniversityA.R. Gado (Author/Creator) - Damanhour UniversityA.F. Khafaga (Author/Creator) - Alexandria UniversityE.O.S. Hussein (Author/Creator) - King Saud UniversityH. Ba-Awadh (Author/Creator)R. Tiwari (Author/Creator) - Uttar Pradesh Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan SansthanK. Dhama (Author/Creator) - Indian Veterinary Research InstituteB. Alhussaini (Author/Creator) - King Abdulaziz UniversityS.R. Alyileili (Author/Creator) - United Arab Emirates UniversityK.A. El-Tarabily (Author/Creator)M.E. Abd El-Hack (Author/Creator)
- Publication Details
- Environmental Science and Pollution Research
- Publisher
- Springer
- Identifiers
- 991005541232407891
- Copyright
- © 2021 The Authors.
- Murdoch Affiliation
- Harry Butler Institute
- Language
- English
- Resource Type
- Journal article
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.104 Virology - General
- 1.104.1353 Coronavirus Research
- Web Of Science research areas
- Environmental Sciences
- ESI research areas
- Environment/Ecology