Journal article
Chagas disease: the challenge of polyparasitism?
Trends in Parasitology, Vol.30(4), pp.176-182
2014
Abstract
The debilitating zoonosis Chagas disease (CD) is caused by infection with the flagellate protozoan Trypanosoma cruzi. One century after its discovery, a curative agent remains elusive. Immune evasion by T. cruzi results in a poorly controlled infection in the host, which can end in either sudden death or a fatal chronic disease that often eventuates after years of an asymptomatic infection. Polyparasitism or mixed/concurrent infections occur more often than not and contribute to the high degree of variability observed across both disease progression and the success of therapeutic interventions. A thorough understanding of the effects of polyparasitism on CD is essential for improving the likelihood of containing, treating, and eventually eliminating CD.
Details
- Title
- Chagas disease: the challenge of polyparasitism?
- Authors/Creators
- C.J. Perez (Author/Creator)A.J. Lymbery (Author/Creator)R.C.A. Thompson (Author/Creator)
- Publication Details
- Trends in Parasitology, Vol.30(4), pp.176-182
- Publisher
- Elsevier BV
- Identifiers
- 991005542360907891
- Copyright
- © 2014 Elsevier Ltd.
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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- Citation topics
- 1 Clinical & Life Sciences
- 1.261 Parasitology - Trypanosoma & Leishmania
- 1.261.596 Trypanosoma Biology
- Web Of Science research areas
- Parasitology
- ESI research areas
- Microbiology