Journal article
Challenges for standardization of Clostridium difficile typing methods
Journal of Clinical Microbiology, Vol.51(9), pp.2810-2814
2013
Abstract
Typing of Clostridium difficile facilitates understanding of the epidemiology of the infection. Some evaluations have shown that certain strain types (for example, ribotype 027) are more virulent than others and are associated with worse clinical outcomes. Although restriction endonuclease analysis (REA) and pulsed-field gel electrophoresis have been widely used in the past, PCR ribotyping is the current method of choice for typing of C. difficile. However, global standardization of ribotyping results is urgently needed. Whole-genome sequencing of C. difficile has the potential to provide even greater epidemiologic information than ribotyping.
Details
- Title
- Challenges for standardization of Clostridium difficile typing methods
- Authors/Creators
- C.A. Huber (Author/Creator) - Royal Brisbane and Women's HospitalN.F. Foster (Author/Creator) - The University of Western AustraliaT.V. Riley (Author/Creator) - The University of Western AustraliaD.L. Paterson (Author/Creator) - Royal Brisbane and Women's Hospital
- Publication Details
- Journal of Clinical Microbiology, Vol.51(9), pp.2810-2814
- Publisher
- American Society for Microbiology
- Identifiers
- 991005540225607891
- Copyright
- © 2013, American Society for Microbiology.
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.120 Inflammatory Bowel Diseases & Infections
- 1.120.1133 Clostridium Infections
- Web Of Science research areas
- Microbiology
- ESI research areas
- Microbiology