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Characteristics of cell fusion induced by a caprine retrovirus
Journal article   Peer reviewed

Characteristics of cell fusion induced by a caprine retrovirus

T.M. Ellis, G.E. Wilcox and W.F. Robinson
Archives of Virology, Vol.86(3-4), pp.263-273
1985
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Abstract

The mechanism of cell-fusion induced by caprine arthritis-encephalitis virus (CAEV) was investigated. Following infection with concentrated CAEV, cell fusion occurred prior to the production of infectious progeny virus. The time of initial detection of cell fusion was dependent on the multiplicity of infection and was not detected until 5 hours after infection. The virus-induced cell fusion was only partially inhibited by ultraviolet irradiation of the virus and was not inhibited by cytosine arabinoside. The results indicated that fusion by CAEV was a slow response to direct interaction of input virus with cells (fusion from without) and that virus replication was not required.

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Citation topics
1 Clinical & Life Sciences
1.66 HIV
1.66.46 HIV Pathogenesis
Web Of Science research areas
Virology
ESI research areas
Microbiology
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