Journal article
Characterization of a simian T-lymphotropic virus from a wild-caught orang-utan (Pongo pygmaeus) from Kalimantan, Indonesia
Journal of General Virology, Vol.79(1), pp.51-55
1998
Abstract
In a recent serological survey among 143 ex-captive orang-utans two individuals were found that reacted positive in an ELISA detecting antibodies which cross-react with human T-lymphotropic virus type I (HTLV-I) antigens. Infection of both animals with an HTLV-I or simian T-lymphotropic virus (STLV)-like virus was confirmed by Western blot analysis. A third wild-caught animal, which was not part of the original serological survey, was also found to be infected with an HTLV-related virus in a diagnostic PCR assay and Western blot assay. Nucleotide sequence analysis of the 709 bp PCR fragment from the tax/rex region of the HTLV/STLV genome confirmed infection of orang-utans with an STLV similar to but clearly distinct from other Asian STLVs.
Details
- Title
- Characterization of a simian T-lymphotropic virus from a wild-caught orang-utan (Pongo pygmaeus) from Kalimantan, Indonesia
- Authors/Creators
- E.J. Verschoor (Author/Creator)K.S. Warren (Author/Creator)H. Niphuis (Author/Creator)Heriyanto (Author/Creator)R.A. Swan (Author/Creator)J.L. Heeney (Author/Creator)
- Publication Details
- Journal of General Virology, Vol.79(1), pp.51-55
- Publisher
- Society for General Microbiology
- Identifiers
- 991005540485707891
- Murdoch Affiliation
- School of Veterinary and Biomedical Sciences
- Language
- English
- Resource Type
- Journal article
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- 1 Clinical & Life Sciences
- 1.66 HIV
- 1.66.1464 HTLV-1/BLV Pathogenesis
- Web Of Science research areas
- Biotechnology & Applied Microbiology
- Virology
- ESI research areas
- Microbiology