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Published (Version of Record)CC BY V4.0, Open Access
Journal article
Chronic Cystoisospora belli infection in an immunocompetent Myanmar refugee - microscopy is not sensitive enough
BMC Infectious Diseases, Vol.16(1), Article number 221
2016
Abstract
Background: Cystoisosporiasis is an opportunistic infection seen more commonly in patients with acquired immunodeficiency syndrome. Although uncommon, Cystoisospora infection can occur in immunocompetent individuals but tend to be benign and self-limiting. Chronic infection however, has been described but diagnosis can often be challenging and requires a high clinical index of suspicion. Case presentation: We present a case of delayed diagnosis of Cystoisospora belli (C. belli) in an immunocompetent 28-year-old refugee from Myanmar. She had a history of chronic diarrhea where exhaustive investigations over many years failed to reveal a diagnosis. Cystoisospora belli cysts were finally detected in stool 4 years after investigation commenced, and PCR testing on stored colon biopsies amplified a molecular product with 99 % sequence homology to C. belli. The patient improved promptly with trimethoprim-sulfamethoxazole treatment. Conclusion: In the appropriate clinical context we suggest molecular testing for C. belli or an empirical therapeutic trial.
Details
- Title
- Chronic Cystoisospora belli infection in an immunocompetent Myanmar refugee - microscopy is not sensitive enough
- Authors/Creators
- S-A Woon (Author/Creator) - Royal Perth HospitalR. Yang (Author/Creator) - Murdoch UniversityU. Ryan (Author/Creator) - Murdoch UniversityP. Boan (Author/Creator) - Royal Perth HospitalD. Prentice (Author/Creator) - Royal Perth Hospital
- Publication Details
- BMC Infectious Diseases, Vol.16(1), Article number 221
- Publisher
- BioMed Central
- Identifiers
- 991005544405807891
- Copyright
- © 2016 Woon et al.
- Murdoch Affiliation
- School of Veterinary and Life Sciences
- Language
- English
- Resource Type
- Journal article
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