Journal article
Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children
Our aim was to describe the epidemiology and incidence of community-onset invasive S. aureus disease in children presenting to our hospital, and to compare the clonal complexes and virulence genes of S. aureus strains causing invasive and non-invasive dis, Vol.142(08), pp.1713-1721
2014
Abstract
Our aim was to describe the epidemiology and incidence of community-onset invasive S. aureus disease in children presenting to our hospital, and to compare the clonal complexes and virulence genes of S. aureus strains causing invasive and non-invasive disease. The virulence gene repertoire of invasive disease isolates was characterized using DNA microarray and compared with the virulence gene repertoire of non-invasive S. aureus isolates. Over the study period, 163 children had an invasive S. aureus infection. There was no difference in the distribution of clonal complexes or in the prevalence of genes encoding virulence factors between invasive and non-invasive isolates. Future research should include a strong focus on identifying the host and environmental factors that, along with organism virulence factors, are contributing to the patterns of invasive S. aureus disease observed in New Zealand.
Details
- Title
- Clinical and molecular epidemiology of community-onset invasive Staphylococcus aureus infection in New Zealand children
- Authors/Creators
- D.A. Williamson (Author/Creator)S.R. Ritchie (Author/Creator)S.A. Roberts (Author/Creator)G.W. Coombs (Author/Creator)M.G. Thomas (Author/Creator)O. Hannaford (Author/Creator)M.G. Baker (Author/Creator)D. Lennon (Author/Creator)J.D. Fraser (Author/Creator)
- Publication Details
- Our aim was to describe the epidemiology and incidence of community-onset invasive S. aureus disease in children presenting to our hospital, and to compare the clonal complexes and virulence genes of S. aureus strains causing invasive and non-invasive dis, Vol.142(08), pp.1713-1721
- Publisher
- Cambridge University Press
- Identifiers
- 991005540440707891
- Copyright
- © Cambridge University Press 2014
- Murdoch Affiliation
- Murdoch University
- Language
- English
- Resource Type
- Journal article
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Source: InCites
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- Collaboration types
- Domestic collaboration
- International collaboration
- Citation topics
- 1 Clinical & Life Sciences
- 1.23 Antibiotics & Antimicrobials
- 1.23.173 MRSA and VRE
- Web Of Science research areas
- Infectious Diseases
- Public, Environmental & Occupational Health
- ESI research areas
- Social Sciences, general