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Clinical presentation and management of suspected ribavirin toxicosis in a dog
Journal article   Peer reviewed

Clinical presentation and management of suspected ribavirin toxicosis in a dog

K. Bridges, N. Beckel, C. Sharp and L. Stern
Canadian Veterinary Journal, Vol.57(5), pp.511-513
2016
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Abstract

A 5-month-old pit bull terrier was presented for evaluation of progressive lethargy, vomiting, diarrhea, and anorexia 45 hours after ingestion of 625 mg/kg body weight (BW) (9000 mg) of the antiviral medication, ribavirin. Abnormalities that were detected included dehydration, tachycardia, elevated liver enzymes, and prolonged prothrombin time. The dog was discharged after 5 days of aggressive supportive care consisting of intravenous fluids, antiemetics, gastroprotectants, hepatoprotectants, dextrose supplementation, and vitamin B/K1 supplementation.

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