Combining quick Sequential Organ Failure Assessment with plasma lactate concentration is comparable to standard Sequential Organ Failure Assessment score in predicting mortality of patients with and without suspected infection

K.M. Ho; N.S.H. Lan

doi:10.1016/j.jcrc.2016.10.005

Back

Combining quick Sequential Organ Failure Assessment with plasma lactate concentration is comparable to standard Sequential Organ Failure Assessment score in predicting mortality of patients with and without suspected infection

Journal article

Open access

Peer reviewed

Combining quick Sequential Organ Failure Assessment with plasma lactate concentration is comparable to standard Sequential Organ Failure Assessment score in predicting mortality of patients with and without suspected infection

K.M. Ho and N.S.H. Lan

Journal of Critical Care, Vol.38, pp.1-5

2017

DOI: https://doi.org/10.1016/j.jcrc.2016.10.005

Files and links (2)

pdf

mortality-of-patients-with-and-without-suspected-infection.pdfDownload View

Author’s VersionCC BY-NC-ND V4.0, Open Access

url

Link to Published Version *Subscription may be requiredView

Abstract

Purpose We sought to determine whether quick Sequential Organ Failure Assessment (qSOFA) score can be used to predict mortality of patients without suspected infection. Materials and methods Using prospectively collected data within the first hour of intensive care unit admission, the predictive ability of qSOFA was compared with the Simplified Acute Physiology Score III, Admission Mortality Prediction Model III, Acute Physiology and Chronic Health Evaluation II model, and standard (full-version) SOFA score using area under the receiver operating characteristic (AUROC) curve and Brier score. Results Of the 2322 patients included, 279 (12.0%) died after intensive care unit admission. The qSOFA score had a modest ability to predict mortality of all critically ill patients (AUROC, 0.672; 95% confidence interval [CI], 0.638-0.707; Brier score 0.099) including the noninfected patients (AUROC, 0.685; 95% CI, 0.637-0.732; Brier score 0.081). The overall predictive ability and calibration of the qSOFA was comparable to other prognostic scores. Combining qSOFA score with lactate concentrations further enhanced its predictive ability (AUROC, 0.730; 95% CI, 0.694-0.765; Brier score 0.097), comparable to the standard SOFA score. Conclusions The qSOFA score had a modest ability to predict mortality of both septic and nonseptic patients; combining qSOFA with plasma lactate had a predictive ability comparable to the standard SOFA score.

Details

Title: Combining quick Sequential Organ Failure Assessment with plasma lactate concentration is comparable to standard Sequential Organ Failure Assessment score in predicting mortality of patients with and without suspected infection
Authors/Creators: K.M. Ho (Author/Creator) - Murdoch University
N.S.H. Lan (Author/Creator) - The University of Western Australia
Publication Details: Journal of Critical Care, Vol.38, pp.1-5
Publisher: Elsevier B.V.
Identifiers: 991005541126907891
Copyright: © 2016 Elsevier Inc.
Murdoch Affiliation: School of Veterinary and Life Sciences
Language: English
Resource Type: Journal article

UN Sustainable Development Goals (SDGs)

This output has contributed to the advancement of the following goals:

Source: InCites

Metrics

251 File views/ downloads

94 Record Views

50 Times Cited - Web of Science

InCites Highlights

These are selected metrics from InCites Benchmarking & Analytics tool, related to this output

Collaboration types: Domestic collaboration
Citation topics: 1 Clinical & Life Sciences; 1.154 Assisted Ventilation; 1.154.360 Procalcitonin
Web Of Science research areas: Critical Care Medicine
ESI research areas: Clinical Medicine