Journal article
Comparative accuracy of two veterinary‐calibrated point‐of‐care glucometres for measurement of blood glucose concentration in dogs
Journal of Small Animal Practice, Vol.63(7), pp.512-519
2022
Abstract
Objectives
To investigate and compare the accuracy of two veterinary portable blood glucose metres (AccuTell; AccubioTech; and AlphaTrak2; Abbott Laboratories).
Materials and Methods
One hundred twenty venous blood samples were obtained for immediate whole blood glucose concentration measurement using two portable blood glucose metres designed for use in dogs. Plasma glucose concentration was measured by a laboratory analyser using a hexokinase reaction method. Packed cell volume was measured for each sample. Linear regression analysis was performed and Bland–Altman plots constructed with International Standards Organisation 15197:2013 standards applied to assess relationship and agreement between results of portable blood glucose metres and laboratory analyser methods, respectively. Clarke's error grid analysis was used to assess clinical accuracy and usefulness.
Results
The AccuTell and the AlphaTrak2 had mean differences of −0.69 ± 0.70 mmol/L (bias ±sd) and −1.09 ± 1.22 mmol/L (bias ± sd) with the reference analyser, respectively. Eighty-eight of 120 (73.3%) samples for the AccuTell, and 73 of 120 (60.8%) samples for the AlphaTrak2 were plotted in the zone of the error grid analysis that indicated less clinical risk of misdiagnosis of glucose status. Neither device fulfilled the International Standards Organisation 15197:2013 standards for system accuracy. A statistically significant effect of packed cell volume was identified on the difference between blood glucose concentration obtained by the AlphaTrak2 and the hexokinase reaction method, but not for the AccuTell.
Clinical Significance
Both devices do not meet International Standards Organisation 15197:2013 standards. Users should expect 95% of the samples measured with the AccuTell to be between −0.7 and +2.1 mmol/L higher than actual values, and 95% of the samples measured with the AlphaTrak2 to be between −1.3 and +3.5 mmol/L higher than actual values.
Details
- Title
- Comparative accuracy of two veterinary‐calibrated point‐of‐care glucometres for measurement of blood glucose concentration in dogs
- Authors/Creators
- G. Wolfenden (Author/Creator) - Animalius Vet, Bayswater, 6053, Australia.F.E. James (Author/Creator) - Animalius Vet, Bayswater, 6053, Australia.L.H.T. Hung (Author/Creator) - Animalius Vet, Bayswater, 6053, Australia.M. Bruce (Author/Creator) - Murdoch UniversityM. Thompson (Author/Creator) - The University of Sydney
- Publication Details
- Journal of Small Animal Practice, Vol.63(7), pp.512-519
- Publisher
- Blackwell Publishing
- Identifiers
- 991005542576607891
- Copyright
- © 2022 British Small Animal Veterinary Association
- Murdoch Affiliation
- Centre for Biosecurity and One Health; School of Veterinary Medicine
- Language
- English
- Resource Type
- Journal article
UN Sustainable Development Goals (SDGs)
This output has contributed to the advancement of the following goals:
Source: InCites
Metrics
47 Record Views
InCites Highlights
These are selected metrics from InCites Benchmarking & Analytics tool, related to this output
- Collaboration types
- Domestic collaboration
- Citation topics
- 3 Agriculture, Environment & Ecology
- 3.232 Veterinary Sciences
- 3.232.1715 Canine Orthopedics
- Web Of Science research areas
- Veterinary Sciences
- ESI research areas
- Plant & Animal Science