Comparison of effects of an endotracheal tube or facemask on breathing pattern and distribution of ventilation in anesthetized horses

F. Moreno-Martinez; D. Byrne; A. Raisis; A.D. Waldmann; G. Hosgood; M. Mosing

doi:10.3389/fvets.2022.895268

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Comparison of effects of an endotracheal tube or facemask on breathing pattern and distribution of ventilation in anesthetized horses

Journal article

Open access

Peer reviewed

Comparison of effects of an endotracheal tube or facemask on breathing pattern and distribution of ventilation in anesthetized horses

F. Moreno-Martinez, D. Byrne, A. Raisis, A.D. Waldmann, G. Hosgood and M. Mosing

Frontiers in Veterinary Science, Vol.9, 895268

2022

DOI: https://doi.org/10.3389/fvets.2022.895268

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Abstract

Equine respiratory physiology might be influenced by the presence of an endotracheal tube (ETT). This experimental, randomized cross-over study aimed to compare breathing pattern (BrP) and ventilation distribution in anesthetized horses spontaneously breathing room air via ETT or facemask (MASK). Six healthy adult horses were anesthetized with total intravenous anesthesia (TIVA; xylazine, ketamine, guaiphenesin), breathing spontaneously in right lateral recumbency, and randomly assigned to ETT or MASK for 30 min, followed by the other treatment for an additional 30 min. During a second anesthesia 1 month later, the treatment order was inversed. Electrical impedance tomography (EIT) using a thoracic electrode belt, spirometry, volumetric capnography, esophageal pressure difference (ΔPoes), venous admixture, and laryngoscopy data were recorded over 2 min every 15 min. Breaths were classified as normal or alternate (sigh or crown-like) according to the EIT impedance curve. A mixed linear model was used to test the effect of treatment on continuous outcomes. Cochran-Mantel-Haenszel analysis was used to test for associations between global BrP and treatment. Global BrP was associated with treatment (p = 0.012) with more alternate breaths during ETT. The center of ventilation right-to-left (CoVRL) showed more ventilation in the non-dependent lung during ETT (p = 0.025). The I:E ratio (p = 0.017) and ΔPoes (p < 0.001) were smaller, and peak expiratory flow (p = 0.009) and physiologic dead space (p = 0.034) were larger with ETT. The presence of an ETT alters BrP and shifts ventilation toward the non-dependent lung in spontaneously breathing horses anesthetized with TIVA.

Details

Title: Comparison of effects of an endotracheal tube or facemask on breathing pattern and distribution of ventilation in anesthetized horses
Authors/Creators: F. Moreno-Martinez (Author/Creator) - Murdoch University
D. Byrne (Author/Creator)
A. Raisis (Author/Creator)
A.D. Waldmann (Author/Creator)
G. Hosgood (Author/Creator)
M. Mosing (Author/Creator)
Publication Details: Frontiers in Veterinary Science, Vol.9, 895268
Publisher: Frontiers Media S.A.
Identifiers: 991005541106107891
Copyright: © 2022 Moreno-Martinez et al.
Murdoch Affiliation: School of Veterinary Medicine
Language: English
Resource Type: Journal article

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Collaboration types: Domestic collaboration; International collaboration
Citation topics: 1 Clinical & Life Sciences; 1.154 Assisted Ventilation; 1.154.277 Mechanical Ventilation
Web Of Science research areas: Veterinary Sciences
ESI research areas: Plant & Animal Science